Dempsey and Makepeace is a British television crime drama made by London Weekend Television for ITV, created and produced by Ranald Graham. The leading roles were played by Michael Brandon and Glynis Barber, who later married each other on 18 November 1989.

The series combined elements of previous series such as the mis-matching of British and American crime-fighters from different classes as seen in The Persuaders! and the action of The Professionals.