Charlene Lee McKenna (Irish: Searlaoin Nic Chionaoith; born March 26, 1984) is an Irish actress.

She became a household name in Ireland after starring as Jennifer Jackson in the miniseries Pure Mule (2005). She appeared on Irish television in Single-Handed 2 (2008), Whistleblower (2008), and Raw (2008–2013).

For Raw, she won Best Actress (Television) at the Irish Film & Television Awards, and for Whistleblower, she won Outstanding Actress in a Mini-Series at the Monte Carlo Television Festival.